YONDELIS® Treatment

Yondelis® Treatment

YONDELIS® is a prescription medicine used to treat people with liposarcoma or leiomyosarcoma that:

  • cannot be treated with surgery or has spread to other areas of the body, and
  • who have received treatment with certain other medicines.

It is not known if YONDELIS® is safe and effective in children.

Receiving YONDELIS®

YONDELIS® is given by a healthcare professional experienced in the use of chemotherapy. Before and between treatments, you will be monitored by your doctor with blood tests.

These tests can help identify side effects and also help your doctor decide what the appropriate dosage of YONDELIS® is for you.

How is YONDELIS® given?

YONDELIS® is given by an intravenous (IV) infusion into a vein over 24 hours. To avoid irritation at the injection site, YONDELIS® is given through a central venous line.

A central venous line is a catheter (tube). It helps you receive your treatment without the need for repeated needle sticks.

Generally, YONDELIS® is given every 3 weeks. If you have side effects, your doctor may recommend a decrease in your dose and/or delay your treatment. If you have any side effects that are severe, your doctor may stop your treatment with YONDELIS®.

Before receiving YONDELIS®, you will be given a steroid medicine that will help reduce the risk of certain side effects.

How can I prepare for infusion treatment?

Talk to your doctor to understand the details about your treatment and ask any questions you may have

Wear comfortable loose-fitting clothes. During the infusion, your vital signs may be monitored (for example, blood pressure and breathing rate). Wearing loose clothes helps the medical team monitor your vital signs

Wear layers of clothing for temperature control. Having layers of clothing lets you control your comfort with the temperature

What can I bring or do to pass the time while getting infusion therapy?


  • Books
  • Magazines
  • Newspapers
  • Crossword puzzles or Sudoku games
  • Smartphone—to play games
  • A neck pillow
  • Pictures of family and loved ones
  • Laptop—to get work done, watch a movie, or play games

Things to do to pass the time:

  • Make your shopping list
  • Knit
  • Crochet
  • Draw or doodle
  • Take a nap
  • Meditate

How long will I be treated with YONDELIS®?

The length of your treatment period will depend on:

  • How your tumor responds
  • Any side effects you may experience

Your doctor may do certain tests while you are taking YONDELIS®. These tests monitor you for side effects and to see how well you are responding to treatment. Your doctor will tell you how long your treatment will last. If you have other questions about this medicine, ask your doctor.

Support during treatment

Find resources to help support you as you undergo treatment with YONDELIS®.



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